PI3K inhibitor LY294002, on the other hand, reversed this impact of puerarin. Puerarin alleviates migration of mesenchymal-like cells by reducing MMPs’ protein expression. Puerarin has protective outcomes on H2O2-induced HCAECs EndMT by cutting down oxidative strain, activating the PI3K/Akt pathway, and restricting mobile migration. Puerarin incl
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